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osome, Continued…
stakeholders and community integrate regulatory perspectives
partners. The data from all of into the exposome science as it
these sources will need to be evolves. In addition, several
integrated and modeled using HERCULES scientists have
a computational platform research programs that use data
(systems biology is a from state agencies such as the
promising starting point). Georgia Department of Natural
The human genome project Resources and the Department of
aimed to discover the genetic Public Health. We anticipate
cause of common diseases. these types of data will play an
Despite the many gene- important contribution as
disease associations HERCULES and its exposome-
identified, however, the
based science develops.
human genome led to the “The Exposome by Michael Community-based
surprising realization that only Waraksa. First appeared in an organizations also participate in
a fraction of disease can be article entitled, “Mapping the the HERCULES Stakeholder
accounted for by genetics. This Exposome” in the September, Board, ensuring that the exposome
highlights the importance of the 2013 issue of Atlanta Magazine. science develops with community
environment in human health. Copyright by Michael Waraksa.” engagement. Importantly,
The exposome complements communities burdened with
and encompasses the genome; gene activity and multiple environmental stressors have a deeper
expression can be induced by the environmental understanding of the exposome. The HERCULES
exposures. community partners have expressed delight that
While the approach, measurement, and the scientists are finally attempting to consider
analysis of the exposome is in early stages of the whole of their reality. These communities are
development, the exposome has immediate intuitively aware that diet, behavior, chemical
practical utility as a tool to initiate the dialogue exposures, stress, any other external forces
among multiple disciplines within and beyond combine to influence their well-being. Scientists
environmental health sciences. By understanding know that these factors leave quantifiable marks
the environmental influences within the on our biological systems. It is time for the
exposome framework, we can make better
science to reflect this reality.
decisions in our personal lives. This framework For More Information:
can assist regulatory agencies with making http://humanexposomeproject.com/
decisions about minimizing the adverse effects on
populations. Environmental Health Professionals http://emoryhercules.com/
from local, state, and federal agencies have joined
the HERCULES Stakeholder Board and will help
Georgia Environmentalist Volume 36 Melanie Pearson, PhD
Director of Community Engagement
PBB Registry
Emory University
1518 Clifton Dr.
Atlanta, GA 30322
17
stakeholders and community integrate regulatory perspectives
partners. The data from all of into the exposome science as it
these sources will need to be evolves. In addition, several
integrated and modeled using HERCULES scientists have
a computational platform research programs that use data
(systems biology is a from state agencies such as the
promising starting point). Georgia Department of Natural
The human genome project Resources and the Department of
aimed to discover the genetic Public Health. We anticipate
cause of common diseases. these types of data will play an
Despite the many gene- important contribution as
disease associations HERCULES and its exposome-
identified, however, the
based science develops.
human genome led to the “The Exposome by Michael Community-based
surprising realization that only Waraksa. First appeared in an organizations also participate in
a fraction of disease can be article entitled, “Mapping the the HERCULES Stakeholder
accounted for by genetics. This Exposome” in the September, Board, ensuring that the exposome
highlights the importance of the 2013 issue of Atlanta Magazine. science develops with community
environment in human health. Copyright by Michael Waraksa.” engagement. Importantly,
The exposome complements communities burdened with
and encompasses the genome; gene activity and multiple environmental stressors have a deeper
expression can be induced by the environmental understanding of the exposome. The HERCULES
exposures. community partners have expressed delight that
While the approach, measurement, and the scientists are finally attempting to consider
analysis of the exposome is in early stages of the whole of their reality. These communities are
development, the exposome has immediate intuitively aware that diet, behavior, chemical
practical utility as a tool to initiate the dialogue exposures, stress, any other external forces
among multiple disciplines within and beyond combine to influence their well-being. Scientists
environmental health sciences. By understanding know that these factors leave quantifiable marks
the environmental influences within the on our biological systems. It is time for the
exposome framework, we can make better
science to reflect this reality.
decisions in our personal lives. This framework For More Information:
can assist regulatory agencies with making http://humanexposomeproject.com/
decisions about minimizing the adverse effects on
populations. Environmental Health Professionals http://emoryhercules.com/
from local, state, and federal agencies have joined
the HERCULES Stakeholder Board and will help
Georgia Environmentalist Volume 36 Melanie Pearson, PhD
Director of Community Engagement
PBB Registry
Emory University
1518 Clifton Dr.
Atlanta, GA 30322
17
